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Distribution: Diazepam is very lipophilic. Though There exists a moderately swift onset of action, the drug swiftly redistributes. Diazepam and its metabolites have significant plasma protein binding.The usefulness of diazepam in long-time period use, that is certainly, in excess of four months, has not been assessed by systematic clinical resear

Diazepam and its metabolites are remarkably certain to plasma proteins (diazepam 98%). Diazepam and its metabolites cross the blood-Mind and placental limitations and may also be located in breast milk in concentrations approximately one particular tenth of People in maternal plasma (times 3 to 9 article-partum).In elderly individuals, it is recomm